ABSTRACT
Malignant fibrous histiocytoma(MFH) is well known as a soft tissue tumor of the extremities and retroperitoneum, but MFH of the skull is very rare. We report a case of MFH arising from the temporal bone in a 27-year-old male. This tumor presented as an osteolytic lesion and soft tissue mass on the left temporal bone without obvious invasion of the underlying brain parenchyma. The patient underwent tumor and bone removal, follwed by radiation therapy. Hostologic examination disclosed pleomorphic spindle cells in a storiform pattern and tumor cells showed positive reaction for vimentin, lysozyme, alpha 1-antitrypsin and (1-antichymotrypsin in immunohistochemical stain.
Subject(s)
Adult , Humans , Male , alpha 1-Antitrypsin , Brain , Extremities , Histiocytoma, Malignant Fibrous , Muramidase , Skull , Temporal Bone , VimentinABSTRACT
Intracerebral sparaganosis, caused by the Plerocercoid of Spirometa mansoni, is very rare. A 54-yeas-old man, who has a history of having eaten raw frogs and snakes 20 years ago, was admitted with 2 years duration of focal seizure and monoparesis on right upper extremity. The brain CT scan and MRI demonstrated extensive and irregular hypodense lesion with punctate calcification in subcortical region of left parietal lobe. A whitish ribbon-like moving parasite could be picked up using CRW stereotactic frame under local anesthesia. On pathological examination was disclosed a sparganum with characteristic calcospherule. Also, preoperative ELISA test for sparganum-specific antibody(IgG) showed positive reaction to sparganum absorbance 1.04 in serum and 0.61 in CSF, respectively(normal abs. : below 0.22). Immediately after removal of parasite, the seizure and motor weakness disappeared. Stereotactic removal of cerebral sparganum can be considered a useful method in selected patients.